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doi: 10.3389/fimmu.2025.1712796 Received 25 September 2025 Revised 25 November 2025 Accepted 25 November 2025 Published 12 December 2025 Volume 16 - 2025 Edited by Remi J Creusot, Columbia University, United States Reviewed by Gustaf Christoffersson, Uppsala University, Sweden Maria Elisabetta Federica Palam, React4life S.p.A, Italy Updates Copyright 2025 Bisconti, Abreu, Nguyen, Stolfi, Corbezzolo, Gigli, Raineri, Cappellano, Polini, Gervaso, Chiocchetti and the FLAMIN-GO Consortium

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Limitations and Uncertainties: A Critical Assessment The lack of robust clinical trials represents the most significant concern

Get medical help right away if you have: Toujeo may have additional side effects including swelling, weight gain, low potassium, and injection site reactions which may include change in fat tissue, skin thickening, redness, swelling, and itching

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Endocrinology 154 : 48